LS-170 |
LS-170 : Covalent Inhibitor of YEATS2
Probe Summary
Selectivity
Potency
In Vivo
Control Compounds
Chemical Information
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Probe Summary
| Targets | Biochemical/Biophysical Potency | Cellular Potency |
|---|---|---|
| YEATS2 |
|
|
Covalent Inhibitor
up to 20 uM
Selectivity
In Cell Selectivity Assessment
Potency Assay Off-Target:
Chemical proteomics approach was employed to determine the selectivity profile of LS-170 at the whol ...
Selectivity Assessment Description:
Among the proteins labeled by Photo-LS-170, only YEATS2 and MBIP were selectively competed by LS-170 ...
Potency Cellular
In Vitro
YEATS2
Mode of Action: Covalent Inhibitor
Structure-Activity-Relationship data available? Yes
DOI Reference: 10.1038/s41589-025-02132-7
Chemical Information
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