GW0742 |
GW072 : Agonist of PPARD
Probe Summary
Selectivity
Potency
In Vivo
Control Compounds
Chemical Information
References
Vendors
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Probe Summary
| Targets | Biochemical/Biophysical Potency | Cellular Potency |
|---|---|---|
| PPARD |
|
|
Agonist
up to 1 uM
Selectivity
In Cell Selectivity Assessment
Potency Assay Off-Target:
Selective in the transient transactivation assay against the other 2 human PPAR subtypes: 1100 nM EC ...
Potency Cellular
In Vitro
PPARD
Mode of Action: Agonist
Structure-Activity-Relationship data available? No
DOI Reference: 10.1016/s0960-894x(03)00207-5
Chemical Information
| Molecular Formula | C21H17F4NO3S2 |
| SMILEs | Cc1cc(SCc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)ccc1OCC(=O)O |
| InChI | InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28) |
| Molecular weight | 471.06 Da |
| AlogP | 6.340540000000006 |
| HBond acceptors | 4 |
| HBond donors | 1 |
| Atoms | 48 |
References
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